Periodontal Disease: The Irreversible Condition Most Dogs Get by Age 3

Pet Dental CarePfizer Animal Health is discontinuing its veterinary periodontal disease vaccine for dogs, called the Porphyromonas-Denticanis-Gulae-Salivosa Bacterin.

The vaccine was conditionally approved for use in the U.S. in 2006, and underwent a four-year study to determine if it produced a long-term reduction in the progression of gum disease in dogs.

Per dvm360:

"The study further confirmed the safety of the vaccine but did not demonstrate a long-term reduction in the progression of periodontal disease when comparing vaccinated dogs and unvaccinated dogs," Pfizer reports. "Based on this important study, Pfizer Animal Health will no longer produce the vaccine after April 6."

According to a Pfizer communication to pet owners, before receiving conditional licensing in 2006 the vaccine was "... extensively tested for safety, and based on initial studies, was shown to have a reasonable expectation of being efficacious."